- Signaling Pathways
- Metabolic Enzyme/Protease
- Acetolactate Synthase (ALS)
Acetolactate Synthase (ALS)
Acetohydroxyacid synthase
Acetohydroxyacid synthase (ALS), a thiamine diphosphate-dependent enzyme, can condense either two pyruvate molecules to form acetolactate for synthesizing Lvaline and L-leucine or pyruvate with 2-ketobutyrate to form acetohydroxybutyrate for synthesizing L-isoleucine. Because the key reaction catalyzed by acetohydroxyacid synthase in the biosynthetic pathways of branched-chain amino acids (valine, leucine, and isoleucine) exists in plants, fungi, archaea, and bacteria, but not in animals, acetohydroxyacid synthase becomes a potential target for developing novel herbicides and antimicrobial compounds.
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Acetolactate Synthase (ALS) Related Products (40)
Related Products (40)
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Nicosulfuron-d6
0 ImagesNicosulfuron-d6 is the deuterium labeled Nicosulfuron. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity. -
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Herbicide safener-2
0 ImagesCat. No.: HY-158245CAS No.: 3027836-84-3Herbicide safener-2 (Compound III-7) is a herbicide safener with the same pharmacokinetic profile as the safener mefenpyr-diethyl (HY-136376). Herbicide safener-2 competitively binds to the acetolactate synthase (ALS) active site with mesosulfuron-methyl (HY-126987). Herbicide safener-2 protects crops against herbicide injury. -
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Pyriftalid (Standard)
0 ImagesCat. No.: HY-112785RCAS No.: 135186-78-6Pyriftalid (Standard) is the analytical standard of Pyriftalid (HY-112785). This product is intended for research and analytical applications. Pyriftalid is one of the most commonly used herbicides that inhibits the synthesis of acetyl lactate synthase (ALS). Pyriftalid is mainly used to prevent poaceae weeds and some broadleaf weeds in paddy fields. -
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Foramsulfuron (Standard)
0 ImagesCat. No.: HY-W422402RCAS No.: 173159-57-4Foramsulfuron (Standard) is the analytical standard of Foramsulfuron. This product is intended for research and analytical applications. Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids. -
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- Pyriftalid
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Chlorsulfuron (Standard)
0 ImagesCat. No.: HY-119737RCAS No.: 64902-72-3Chlorsulfuron (Standard) is the analytical standard of Chlorsulfuron (HY-119737). This product is intended for research and analytical applications. Chlorsulfuron is an acetolactate synthase inhibitor and selective systemic herbicide. Chlorsulfuron blocks the synthesis of branched-chain amino acids (valine and isoleucine), thereby inhibiting protein synthesis, cell growth, and cell division. Chlorsulfuron blocks G1 and G2 phase cell cycle progression in plant root tip cells without directly interfering with mitosis or DNA synthesis. Chlorsulfuron completely inhibits germination of non-target terrestrial plants and is highly toxic to aquatic macrophytes. Chlorsulfuron has low toxicity to mammals, birds and bees, and moderate toxicity to fish and aquatic invertebrates. Chlorsulfuron can be used in studies related to herbicides, plant cell cycles and ecotoxicology. -
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Prosulfuron
0 ImagesCat. No.: HY-W040279CAS No.: 94125-34-5Prosulfuron is a fluorinated sulfonylurea herbicide with a reported acute oral LD50 of 546 mg/kg in female rats. Prosulfuron acts by inhibiting acetolactate synthase (ALS) to block the biosynthesis of branched-chain amino acids (valine, leucine and isoleucine) in plants, thereby suppressing weed growth. Prosulfuron may disrupt the soil microbial community balance in alkaline soils with minimal chemical degradation. Prosulfuron has low toxicity to humans and mammals, and can be used for the research of broadleaf weed control in maize and sweet corn. -
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Pyrimisulfan
0 ImagesCat. No.: HY-W721333CAS No.: 221205-90-9Pyrimisulfan is a potent acetolactate synthase (ALS) inhibitor and a broad‑spectrum herbicide. Pyrimisulfan selectively inhibits plant acetolactate synthase. Pyrimisulfan controls a wide spectrum of paddy weeds including annual grasses, sedges, broadleaf weeds, and sulfonylurea‑resistant biotypes pre‑ and postemergence, with long residual activity and excellent rice safety. Pyrimisulfan can be used for research on paddy herbicides. -
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Primisulfuron-methyl
0 ImagesCat. No.: HY-W482133CAS No.: 86209-51-0Primisulfuron-methyl is a herbicide. Primisulfuron-methyl shows inhibitory activity against acetolactate synthase (ALS) enzyme. Primisulfuron-methyl can be used to selectively control annual bluegrass of Kentucky bluegrass turf. -
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Pyroxsulam
0 ImagesPyroxsulam is a selective, foliar-applied acetolactate synthase (ALS)-inhibiting herbicide. Pyroxsulam can be used for the study of grassy weed management in winter wheat systems. -
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Foramsulfuron
0 ImagesCat. No.: HY-W422402CAS No.: 173159-57-4Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids. -
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Cloransulam-methyl (Standard)
0 ImagesCloransulam-methyl (Standard) is the analytical standard of Cloransulam-methyl. This product is intended for research and analytical applications. Cloransulam-methyl is a triazolopyrimidine sulfonanilide herbicide. Cloransulam-methyl can be used to control broadleaf weeds in soybean by acetolactate synthase (ALS) inhibition. -
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Bispyribac
0 ImagesCat. No.: HY-B0869CAS No.: 125401-75-4Bispyribac is an acetolactate synthase inhibitor that can be used as a systemic post-emergence herbicide for control of weeds in agriculture. Bispyribac blocks the amino acid synthesis. Bispyribac has low acute toxicity in animal models. -
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Penoxsulam
0 ImagesCat. No.: HY-135713CAS No.: 219714-96-2Penoxsulam is an acetolactate synthase (ALS) inhibitor herbicide. Penoxsulam inhibits Candida auris acetohydroxyacid synthase (AHAS) with a Ki value of <32 nM. Penoxsulam can be used for postemergence control of annual grasses, sedges, and broadleaf weeds in rice culture. Penoxsulam can be used for the study of Candida auris infections. -
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(E)-Pyriminobac-methyl
0 ImagesCat. No.: HY-W681876CAS No.: 147411-69-6(E)-Pyriminobac-methyl is an Acetolactate synthase inhibitor and a pyrimidinylbenzoate Herbicide. (E)-Pyriminobac-methyl inhibits acetolactate synthase and blocks the biosynthesis of branched-chain amino acids. The herbicidal activity of (E)-Pyriminobac-methyl against Echinochloa crus-galli and Leptochloa chinensis is 1.5-2 times higher than that of Bensulfuron-methyl (HY-B0870). -
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Mesosulfuron-methyl (Standard)
0 ImagesCat. No.: HY-126987RCAS No.: 208465-21-8Mesosulfuron-methyl (Standard) is the analytical standard of Mesosulfuron-methyl. This product is intended for research and analytical applications. Mesosulfuron-methyl is a sulfonylurea herbicide that inhibits acetolactate synthase (ALS) and is used in research for post-emergence control of ryegrass and Avena spp. (wild oat) in wheat fields. -
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Herbicide safener-4
0 ImagesCat. No.: HY-170920CAS No.: 3056059-99-2Herbicide safener-4 is a herbicide safener targeting acetolactate synthase (ALS). Herbicide safener-4 competitively binds to the active site of ALS, blocks the binding of Mesosulfuron-methyl (HY-126987), and simultaneously allows substrates to enter for catalytic reactions. Herbicide safener-4 increases the content/activity of glutathione (GSH), glutathione S-transferase (GST), cytochrome P450 monooxygenase (CYP450) and peroxidase (POD) in plants, and decreases the activity of superoxide dismutase (SOD). -
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Metazosulfuron
0 ImagesCat. No.: HY-W708945CAS No.: 868680-84-6Metazosulfuron is an acetolactate synthase (ALS)-inhibiting herbicide. Metazosulfuron provides complete control of pondweed (Potamogeton nodosus) and prevents its regrowth in transplanted rice ecosystems. Metazosulfuron contributes to increased rough rice grain. -
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Bispyribac sodium (Standard)
0 ImagesCat. No.: HY-B0869ARCAS No.: 125401-92-5Bispyribac (sodium) (Standard) is the analytical standard of Bispyribac sodium (HY-B0869A). This product is intended for research and analytical applications. Bispyribac sodium is a selective, orally active, systemic and post-emergence herbicide. Bispyribac sodium reduces SOD levels and inhibits ALS activity. Bispyribac sodium blocks the biosynthesis of branched-chain amino acids, resulting in growth retardation, chlorosis and necrosis of weeds. Bispyribac sodium exerts herbicidal activity against grass, sedge and broadleaf weeds in rice fields. Bispyribac sodium is hepatotoxic and genotoxic. -
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Pyrazosulfuron-ethyl (Standard)
0 ImagesCat. No.: HY-B0865RCAS No.: 93697-74-6Pyrazosulfuron-ethyl (Standard) is the analytical standard of Pyrazosulfuron-ethyl. This product is intended for research and analytical applications. Pyrazosulfuron-ethyl, one of the acetolactate synthase inhibiting herbicides in the sulphonylurea family, has been widely used to control weed growth in commercial cereal, soybean, and vegetable fields. -
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